HZ is a painful rash that results from reactivation of the latent varicella-zoster virus (VZV). Primary infection with VZV causes chickenpox.1,2
Approximately 99.5% of adults in the US born before 1980 have been infected with VZV and are at risk of developing HZ. An estimated 1 million people develop HZ annually in the US. The risk of HZ increases with age.1